OraGRAFT® Prime

OraGraft Prime is 100% bone fibers, demineralized to encourage bone formation and healing.

Applications/Indications

OraGraft Prime can be used in a variety of dental bone grafting procedures as per the dentist’s preference and clinical judgement:

  • Socket preservation
  • Ridge augmentation
  • As a graft enhancer in a sinus lift
  • A preferred option is for the treatment of periodontal osseous defects particularly for saving natural teeth

Why use / Benefits

  • 100% Bone: Facilitates natural remodeling during the bone healing process (no human, xenograft or synthetic carriers)
  • Osteoconductive: The large surface area and interconnected network of demineralized cortical fibers provide a scaffold that promotes cellular attachment and cell spreading1
  • Osteoinductive Potential: Optimally demineralized by LifeNet Health’s patented and proprietary PAD® technology to expose natural growth factors2-6
  • Versatile: Moldable upon rehydration to conform to the surgical site
  • Resists Migration: Interlocking fibers allow graft to remain intact and in place
  • Safety: Sterilized using proprietary and patented Allowash XG® technology, providing a sterility assurance level of 10-6 to reduce the risk of disease transmission without compromising the graft’s inherent osteoconductive properties or osteoinductive potential7
  • Convenience: Ambient storage and rapid rehydration

Available in:

  • 0,5 cc
  • 1,0 cc
  • 2,5 cc

References:
1. Murphy MB, Suzuki RK, Sand TT, et al. Short term culture of mesenchymal stem cells with commercial osteoconductive carriers provides unique insights into biocompatibility. J Clin. Med. 2013; 2,49-66; doi:10.3390/jcm2030049
2. Zhang M, Powers RM, and Wolfinbarger L. Effect(s) of the demineralization process on the osteoinductivity of demineralized bone matrix. J Periodontol. 1997; 68:1085-1092
3. Turonis JW, McPherson JC 3rd, Cuenin MF, et al. The effect of residual calcium in decalcified freeze-dried bone allograft in a criticalsized defect in the Rattus norvegicus calvarium. J Oral Implantol. 2006; 32(2):55-62
4. Herold RW, Pashley DH, Cuenin MF, et al. The effects of Varying degrees of Allograft Decalcification on Cultured Porcine Osteoclast cells. J Periodontol. 2002 Feb; 73(2):213-9
5. Mott DA, Mailhot J, Cuenin MF, et al. Enhancement of osteoblast proliferation in vitro by selective enrichment of demineralized freeze-dried bone allograft with specific growth factors. J Oral Implantol. 2002; 28(2):57-66
6. Pietrzak WS, Ali SN, Chitturi D, et al. BMP depletion occurs during prolonged acid demineralization of bone: characterization and implications for graft preparation. Cell Tiss. Bank. 2007 (Published on line)
7. Eisenlohr LM. “Allograft Tissue Sterilization Using Allowash XG(R).” 2007 Bio-Implants Brief.

OraGRAFT® Prime - 100% αφαλατωµένες προσαρµοζόµενες οστικές ίνες